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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MORC2
Full Name:
MORC family CW-type zinc finger protein 2
Alias:
AC004542.C22.1; KIAA0852; MORC family CW-type zinc finger 2; ZCW3; ZCWCC1; Zinc finger CW-type coiled-coil domain protein 1
Type:
Unknown function
Mass (Da):
117823
Number AA:
1032
UniProt ID:
Q9Y6X9
International Prot ID:
IPI00455518
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
S
L
N
R
A
Q
L
T
F
E
Y
L
H
T
N
Site 2
Y18
R
A
Q
L
T
F
E
Y
L
H
T
N
S
T
T
Site 3
T21
L
T
F
E
Y
L
H
T
N
S
T
T
H
E
F
Site 4
T24
E
Y
L
H
T
N
S
T
T
H
E
F
L
F
G
Site 5
T46
N
A
R
D
A
D
A
T
R
I
D
I
Y
A
E
Site 6
Y51
D
A
T
R
I
D
I
Y
A
E
R
R
E
D
L
Site 7
S76
D
G
A
G
M
D
P
S
D
A
A
S
V
I
Q
Site 8
S80
M
D
P
S
D
A
A
S
V
I
Q
F
G
K
S
Site 9
S87
S
V
I
Q
F
G
K
S
A
K
R
T
P
E
S
Site 10
T91
F
G
K
S
A
K
R
T
P
E
S
T
Q
I
G
Site 11
S94
S
A
K
R
T
P
E
S
T
Q
I
G
Q
Y
G
Site 12
T95
A
K
R
T
P
E
S
T
Q
I
G
Q
Y
G
N
Site 13
S106
Q
Y
G
N
G
L
K
S
G
S
M
R
I
G
K
Site 14
S108
G
N
G
L
K
S
G
S
M
R
I
G
K
D
F
Site 15
T126
T
K
K
E
D
T
M
T
C
L
F
L
S
R
T
Site 16
T133
T
C
L
F
L
S
R
T
F
H
E
E
E
G
I
Site 17
Y175
E
T
E
L
I
Y
K
Y
S
P
F
R
T
E
E
Site 18
S176
T
E
L
I
Y
K
Y
S
P
F
R
T
E
E
E
Site 19
T180
Y
K
Y
S
P
F
R
T
E
E
E
V
M
T
Q
Site 20
T186
R
T
E
E
E
V
M
T
Q
F
M
K
I
P
G
Site 21
S218
E
P
E
L
D
I
I
S
N
P
R
D
I
Q
M
Site 22
S229
D
I
Q
M
A
E
T
S
P
E
G
T
K
P
E
Site 23
T233
A
E
T
S
P
E
G
T
K
P
E
R
R
S
F
Site 24
S239
G
T
K
P
E
R
R
S
F
R
A
Y
A
A
V
Site 25
Y243
E
R
R
S
F
R
A
Y
A
A
V
L
Y
I
D
Site 26
S268
K
V
Q
T
K
R
L
S
C
C
L
Y
K
P
R
Site 27
Y272
K
R
L
S
C
C
L
Y
K
P
R
M
Y
K
Y
Site 28
Y277
C
L
Y
K
P
R
M
Y
K
Y
T
S
S
R
F
Site 29
Y279
Y
K
P
R
M
Y
K
Y
T
S
S
R
F
K
T
Site 30
T280
K
P
R
M
Y
K
Y
T
S
S
R
F
K
T
R
Site 31
S281
P
R
M
Y
K
Y
T
S
S
R
F
K
T
R
A
Site 32
S282
R
M
Y
K
Y
T
S
S
R
F
K
T
R
A
E
Site 33
T286
Y
T
S
S
R
F
K
T
R
A
E
Q
E
V
K
Site 34
S311
E
K
A
R
E
A
E
S
K
A
R
T
L
E
V
Site 35
T315
E
A
E
S
K
A
R
T
L
E
V
R
L
G
G
Site 36
T325
V
R
L
G
G
D
L
T
R
D
S
R
V
M
L
Site 37
S328
G
G
D
L
T
R
D
S
R
V
M
L
R
Q
V
Site 38
T341
Q
V
Q
N
R
A
I
T
L
R
R
E
A
D
V
Site 39
Y394
C
S
R
L
I
K
M
Y
E
K
V
G
P
Q
L
Site 40
Y450
M
G
E
H
L
A
Q
Y
W
K
D
I
A
I
A
Site 41
S480
A
N
W
N
Q
P
P
S
S
E
L
R
Y
K
R
Site 42
S481
N
W
N
Q
P
P
S
S
E
L
R
Y
K
R
R
Site 43
Y485
P
P
S
S
E
L
R
Y
K
R
R
R
A
M
E
Site 44
T507
D
L
C
L
K
W
R
T
L
P
F
Q
L
S
S
Site 45
S513
R
T
L
P
F
Q
L
S
S
V
E
K
D
Y
P
Site 46
S514
T
L
P
F
Q
L
S
S
V
E
K
D
Y
P
D
Site 47
Y519
L
S
S
V
E
K
D
Y
P
D
T
W
V
C
S
Site 48
T549
K
Q
K
V
P
L
G
T
F
R
K
D
M
K
T
Site 49
T556
T
F
R
K
D
M
K
T
Q
E
E
K
Q
K
Q
Site 50
T582
L
E
A
L
Q
K
T
T
P
I
R
S
Q
A
D
Site 51
S586
Q
K
T
T
P
I
R
S
Q
A
D
L
K
K
L
Site 52
T598
K
K
L
P
L
E
V
T
T
R
P
S
T
E
E
Site 53
S602
L
E
V
T
T
R
P
S
T
E
E
P
V
R
R
Site 54
T603
E
V
T
T
R
P
S
T
E
E
P
V
R
R
P
Site 55
S615
R
R
P
Q
R
P
R
S
P
P
L
P
A
V
I
Site 56
S627
A
V
I
R
N
A
P
S
R
P
P
S
L
P
T
Site 57
S631
N
A
P
S
R
P
P
S
L
P
T
P
R
P
A
Site 58
T634
S
R
P
P
S
L
P
T
P
R
P
A
S
Q
P
Site 59
S639
L
P
T
P
R
P
A
S
Q
P
R
K
A
P
V
Site 60
S648
P
R
K
A
P
V
I
S
S
T
P
K
L
P
A
Site 61
S649
R
K
A
P
V
I
S
S
T
P
K
L
P
A
L
Site 62
T650
K
A
P
V
I
S
S
T
P
K
L
P
A
L
A
Site 63
S663
P
V
V
K
K
T
E
S
P
I
K
L
S
P
A
Site 64
T664
A
A
R
E
E
A
S
T
S
R
L
L
Q
P
P
Site 65
S665
A
R
E
E
A
S
T
S
R
L
L
Q
P
P
E
Site 66
T680
A
P
R
K
P
A
N
T
L
V
K
T
A
S
R
Site 67
T684
P
A
N
T
L
V
K
T
A
S
R
P
A
P
L
Site 68
S686
N
T
L
V
K
T
A
S
R
P
A
P
L
V
Q
Site 69
S696
A
P
L
V
Q
Q
L
S
P
S
L
L
P
N
S
Site 70
S698
L
V
Q
Q
L
S
P
S
L
L
P
N
S
K
S
Site 71
S703
S
P
S
L
L
P
N
S
K
S
P
R
E
V
P
Site 72
S705
S
L
L
P
N
S
K
S
P
R
E
V
P
S
P
Site 73
S711
K
S
P
R
E
V
P
S
P
K
V
I
K
T
P
Site 74
T717
P
S
P
K
V
I
K
T
P
V
V
K
K
T
E
Site 75
T723
K
T
P
V
V
K
K
T
E
S
P
I
K
L
S
Site 76
S725
P
V
V
K
K
T
E
S
P
I
K
L
S
P
A
Site 77
S730
T
E
S
P
I
K
L
S
P
A
T
P
S
R
K
Site 78
T733
P
I
K
L
S
P
A
T
P
S
R
K
R
S
V
Site 79
S735
K
L
S
P
A
T
P
S
R
K
R
S
V
A
V
Site 80
S739
A
T
P
S
R
K
R
S
V
A
V
S
D
E
E
Site 81
S743
R
K
R
S
V
A
V
S
D
E
E
E
V
E
E
Site 82
S773
V
K
E
E
K
K
D
S
N
E
L
S
D
S
A
Site 83
S777
K
K
D
S
N
E
L
S
D
S
A
G
E
E
D
Site 84
S779
D
S
N
E
L
S
D
S
A
G
E
E
D
S
A
Site 85
S785
D
S
A
G
E
E
D
S
A
D
L
K
R
A
Q
Site 86
Y808
V
R
V
N
R
E
W
Y
T
G
R
V
T
A
V
Site 87
T813
E
W
Y
T
G
R
V
T
A
V
E
V
G
K
H
Site 88
Y830
R
W
K
V
K
F
D
Y
V
P
T
D
T
T
P
Site 89
T836
D
Y
V
P
T
D
T
T
P
R
D
R
W
V
E
Site 90
S856
V
R
L
M
K
P
P
S
P
E
H
Q
S
L
D
Site 91
S861
P
P
S
P
E
H
Q
S
L
D
T
Q
Q
E
G
Site 92
T864
P
E
H
Q
S
L
D
T
Q
Q
E
G
G
E
E
Site 93
S889
A
V
A
E
P
S
T
S
E
C
L
R
I
E
P
Site 94
T898
C
L
R
I
E
P
D
T
T
A
L
S
T
N
H
Site 95
T899
L
R
I
E
P
D
T
T
A
L
S
T
N
H
E
Site 96
S902
E
P
D
T
T
A
L
S
T
N
H
E
T
I
D
Site 97
S926
L
R
Y
F
L
P
P
S
F
P
I
S
K
K
Q
Site 98
S930
L
P
P
S
F
P
I
S
K
K
Q
L
S
A
M
Site 99
S935
P
I
S
K
K
Q
L
S
A
M
N
S
D
E
L
Site 100
S939
K
Q
L
S
A
M
N
S
D
E
L
I
S
F
P
Site 101
S944
M
N
S
D
E
L
I
S
F
P
L
K
E
Y
F
Site 102
Y950
I
S
F
P
L
K
E
Y
F
K
Q
Y
E
V
G
Site 103
Y954
L
K
E
Y
F
K
Q
Y
E
V
G
L
Q
N
L
Site 104
S964
G
L
Q
N
L
C
N
S
Y
Q
S
R
A
D
S
Site 105
Y965
L
Q
N
L
C
N
S
Y
Q
S
R
A
D
S
R
Site 106
S967
N
L
C
N
S
Y
Q
S
R
A
D
S
R
A
K
Site 107
S971
S
Y
Q
S
R
A
D
S
R
A
K
A
S
E
E
Site 108
S979
R
A
K
A
S
E
E
S
L
R
T
S
E
R
K
Site 109
T982
A
S
E
E
S
L
R
T
S
E
R
K
L
R
E
Site 110
S983
S
E
E
S
L
R
T
S
E
R
K
L
R
E
T
Site 111
T990
S
E
R
K
L
R
E
T
E
E
K
L
Q
K
L
Site 112
T999
E
K
L
Q
K
L
R
T
N
I
V
A
L
L
Q
Site 113
T1016
Q
E
D
I
D
I
N
T
D
D
E
L
D
A
Y
Site 114
Y1023
T
D
D
E
L
D
A
Y
I
E
D
L
I
T
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation