PhosphoNET

           
Protein Info 
   
Short Name:  MCR
Full Name:  Mineralocorticoid receptor
Alias:  MLR; MR; NR3C2; nuclear receptor subfamily 3, group C, member 2
Type:  Receptor, nuclear
Mass (Da):  107067
Number AA:  984
UniProt ID:  P08235
International Prot ID:  IPI00027744
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0019898  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0043565  GO:0005496 PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0007165  GO:0006350 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y6__METKGYHSLPEGL
Site 2S8METKGYHSLPEGLDM
Site 3S23ERRWGQVSQAVERSS
Site 4S30SQAVERSSLGPTERT
Site 5T34ERSSLGPTERTDENN
Site 6S59SGAIPNNSTQGSSKE
Site 7T60GAIPNNSTQGSSKEK
Site 8S63PNNSTQGSSKEKQEL
Site 9T85NNRPGILTSDIKTEL
Site 10S86NRPGILTSDIKTELE
Site 11T90ILTSDIKTELESKEL
Site 12S98ELESKELSATVAESM
Site 13T100ESKELSATVAESMGL
Site 14Y108VAESMGLYMDSVRDA
Site 15S111SMGLYMDSVRDADYS
Site 16Y117DSVRDADYSYEQQNQ
Site 17S118SVRDADYSYEQQNQQ
Site 18Y119VRDADYSYEQQNQQG
Site 19S129QNQQGSMSPAKIYQN
Site 20Y134SMSPAKIYQNVEQLV
Site 21S152KGNGHRPSTLSCVNT
Site 22T153GNGHRPSTLSCVNTP
Site 23S155GHRPSTLSCVNTPLR
Site 24S163CVNTPLRSFMSDSGS
Site 25S166TPLRSFMSDSGSSVN
Site 26S168LRSFMSDSGSSVNGG
Site 27S170SFMSDSGSSVNGGVM
Site 28S191PIMCHEKSPSVCSPL
Site 29S196EKSPSVCSPLNMTSS
Site 30S212CSPAGINSVSSTTAS
Site 31S227FGSFPVHSPITQGTP
Site 32T233HSPITQGTPLTCSPN
Site 33T236ITQGTPLTCSPNAEN
Site 34S238QGTPLTCSPNAENRG
Site 35S246PNAENRGSRSHSPAH
Site 36S248AENRGSRSHSPAHAS
Site 37S250NRGSRSHSPAHASNV
Site 38S255SHSPAHASNVGSPLS
Site 39S259AHASNVGSPLSSPLS
Site 40S262SNVGSPLSSPLSSMK
Site 41S263NVGSPLSSPLSSMKS
Site 42S266SPLSSPLSSMKSSIS
Site 43S267PLSSPLSSMKSSISS
Site 44S270SPLSSMKSSISSPPS
Site 45S271PLSSMKSSISSPPSH
Site 46S273SSMKSSISSPPSHCS
Site 47S274SMKSSISSPPSHCSV
Site 48S277SSISSPPSHCSVKSP
Site 49S280SSPPSHCSVKSPVSS
Site 50S283PSHCSVKSPVSSPNN
Site 51S286CSVKSPVSSPNNVTL
Site 52S287SVKSPVSSPNNVTLR
Site 53T292VSSPNNVTLRSSVSS
Site 54S295PNNVTLRSSVSSPAN
Site 55S296NNVTLRSSVSSPANI
Site 56S298VTLRSSVSSPANINN
Site 57S299TLRSSVSSPANINNS
Site 58S306SPANINNSRCSVSSP
Site 59S309NINNSRCSVSSPSNT
Site 60S311NNSRCSVSSPSNTNN
Site 61S312NSRCSVSSPSNTNNR
Site 62S314RCSVSSPSNTNNRST
Site 63T316SVSSPSNTNNRSTLS
Site 64S320PSNTNNRSTLSSPAA
Site 65T321SNTNNRSTLSSPAAS
Site 66S323TNNRSTLSSPAASTV
Site 67S324NNRSTLSSPAASTVG
Site 68S342SPVNNAFSYTASGTS
Site 69Y343PVNNAFSYTASGTSA
Site 70T344VNNAFSYTASGTSAG
Site 71S346NAFSYTASGTSAGSS
Site 72T348FSYTASGTSAGSSTL
Site 73S349SYTASGTSAGSSTLR
Site 74S353SGTSAGSSTLRDVVP
Site 75T354GTSAGSSTLRDVVPS
Site 76S361TLRDVVPSPDTQEKG
Site 77T364DVVPSPDTQEKGAQE
Site 78T377QEVPFPKTEEVESAI
Site 79S385EEVESAISNGVTGQL
Site 80Y397GQLNIVQYIKPEPDG
Site 81S407PEPDGAFSSSCLGGN
Site 82S408EPDGAFSSSCLGGNS
Site 83S409PDGAFSSSCLGGNSK
Site 84S415SSCLGGNSKINSDSS
Site 85S419GGNSKINSDSSFSVP
Site 86S421NSKINSDSSFSVPIK
Site 87S422SKINSDSSFSVPIKQ
Site 88S424INSDSSFSVPIKQES
Site 89S431SVPIKQESTKHSCSG
Site 90S435KQESTKHSCSGTSFK
Site 91S437ESTKHSCSGTSFKGN
Site 92T439TKHSCSGTSFKGNPT
Site 93S440KHSCSGTSFKGNPTV
Site 94T446TSFKGNPTVNPFPFM
Site 95Y457FPFMDGSYFSFMDDK
Site 96Y466SFMDDKDYYSLSGIL
Site 97Y467FMDDKDYYSLSGILG
Site 98S468MDDKDYYSLSGILGP
Site 99S470DKDYYSLSGILGPPV
Site 100S487FDGNCEGSGFPVGIK
Site 101S501KQEPDDGSYYPEASI
Site 102Y502QEPDDGSYYPEASIP
Site 103Y503EPDDGSYYPEASIPS
Site 104S518SAIVGVNSGGQSFHY
Site 105S522GVNSGGQSFHYRIGA
Site 106Y525SGGQSFHYRIGAQGT
Site 107T532YRIGAQGTISLSRSA
Site 108S534IGAQGTISLSRSARD
Site 109S536AQGTISLSRSARDQS
Site 110S538GTISLSRSARDQSFQ
Site 111S543SRSARDQSFQHLSSF
Site 112S548DQSFQHLSSFPPVNT
Site 113S549QSFQHLSSFPPVNTL
Site 114T555SSFPPVNTLVESWKS
Site 115S562TLVESWKSHGDLSSR
Site 116S567WKSHGDLSSRRSDGY
Site 117S568KSHGDLSSRRSDGYP
Site 118S571GDLSSRRSDGYPVLE
Site 119Y574SSRRSDGYPVLEYIP
Site 120Y579DGYPVLEYIPENVSS
Site 121S585EYIPENVSSSTLRSV
Site 122S587IPENVSSSTLRSVST
Site 123T588PENVSSSTLRSVSTG
Site 124S591VSSSTLRSVSTGSSR
Site 125S593SSTLRSVSTGSSRPS
Site 126T594STLRSVSTGSSRPSK
Site 127S596LRSVSTGSSRPSKIC
Site 128S597RSVSTGSSRPSKICL
Site 129S600STGSSRPSKICLVCG
Site 130Y615DEASGCHYGVVTCGS
Site 131Y637AVEGQHNYLCAGRND
Site 132S675MNLGARKSKKLGKLK
Site 133S703PPPPPPQSPEEGTTY
Site 134Y710SPEEGTTYIAPAKEP
Site 135S731VPQLSTISRALTPSP
Site 136T735STISRALTPSPVMVL
Site 137S737ISRALTPSPVMVLEN
Site 138Y751NIEPEIVYAGYDSSK
Site 139Y754PEIVYAGYDSSKPDT
Site 140S757VYAGYDSSKPDTAEN
Site 141T761YDSSKPDTAENLLST
Site 142S767DTAENLLSTLNRLAG
Site 143S815CLSSFALSWRSYKHT
Site 144S818SFALSWRSYKHTNSQ
Site 145Y819FALSWRSYKHTNSQF
Site 146S824RSYKHTNSQFLYFAP
Site 147S888IPKDGLKSQAAFEEM
Site 148T897AAFEEMRTNYIKELR
Site 149Y899FEEMRTNYIKELRKM
Site 150T908KELRKMVTKCPNNSG
Site 151Y922GQSWQRFYQLTKLLD
Site 152S930QLTKLLDSMHDLVSD
Site 153Y944DLLEFCFYTFRESHA
Site 154S973DQLPKVESGNAKPLY
Site 155Y980SGNAKPLYFHRK___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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